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Article

Genome-wide transposon mutagenesis of Borrelia burgdorferi for identification of phenotypic mutants.

Applied and environmental microbiology - 1 Oct 2004

Stewart Philip E, Hoff Jessica, Fischer Elizabeth, Krum Jonathan G, Rosa Patricia A

Abstract excerpt

The spirochete Borrelia burgdorferi is the causative agent of Lyme disease, the leading vector-borne illness in the United States. Many of the genetic factors affecting spirochete morphology and physiology are unknown due to the limited genetic tools available and the large number of open reading frames with unknown functions. By adapting a mariner transposon to function in B. burgdorferi, we have developed a...

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Identifiers

PMID: 15466540
DOI: 10.1128/AEM.70.10.5973-5979.2004
PMCID: PMC522107

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Source receipt: pubmed, retrieved 7 Sept 2026.

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