Article
Genome-Wide Mutagenesis in Borrelia burgdorferi.
Methods in molecular biology (Clifton, N.J.) - 1 Jan 2018
Lin Tao, Gao Lihui
Abstract excerpt
Signature-tagged mutagenesis (STM) is a functional genomics approach to identify bacterial virulence determinants and virulence factors by simultaneously screening multiple mutants in a single host animal, and has been utilized extensively for the study of bacterial pathogenesis, host-pathogen interactions, and spirochete and tick biology. The signature-tagged transposon mutagenesis has been developed to...
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