Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Insight of host immune evasion mediated by two variants of group a Streptococcus Mac protein.

The Journal of biological chemistry - 10 Dec 2004

Agniswamy Johnson, Lei Benfang, Musser James M, Sun Peter D

Abstract excerpt

Group A Streptococcus has evolved numerous mechanisms to evade the host immune system to survive, disseminate, and cause disease. Recently a secreted protein named Mac-1 was identified and shown to enhance survival of the pathogen. A new variant of Mac-1 (designated Mac-2) also was recently described and shown to differ from Mac-1 by approximately 50% amino acid sequence divergence in the middle one-third of the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Genes, Bacterial
Share to Immunoglobulin Fc Fragments

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Immunoglobulin G

Share to In Vitro Techniques

Share to Kinetics

Share to Models, Immunological

Share to Receptors, IgG

Share to Streptococcus pyogenes

Source

Identifiers

PMID: 15466462
DOI: 10.1074/jbc.M410698200

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Insight of host immune evasion mediated by two variants of group a Streptococcus Mac protein.PMID 15466462Read ↗

Opsonophagocytosis-inhibiting mac protein of group a streptococcus: identification and characteristics of two genetic complexes.Semantic proximity Read ↗

The type-2 Streptococcus canis M protein SCM-2 binds fibrinogen and facilitates antiphagocytic propertiesSemantic proximity Read ↗

Neisseria meningitidis IgA1-specific serine protease exhibits novel cleavage activity against IgG3Semantic proximity Read ↗

The putative proteinase maturation protein A of Streptococcus pneumoniae is a conserved surface protein with potential to elicit protective immune responses.Semantic proximity Read ↗

Nonimmune antibody interactions of Group A Streptococcus M and M-like proteinsSemantic proximity Read ↗

A quantitative Streptococcus pyogenes–human protein–protein interaction map reveals localization of opsonizing antibodiesSemantic proximity Read ↗

Evasion of Phagocytosis through Cooperation between Two Ligand-binding Regions in <i>Streptococcus pyogenes</i> M ProteinSemantic proximity Read ↗

Soluble MAC is primarily released from MAC-resistant bacteria that potently convert complement component C5Semantic proximity Read ↗

In silico analysis of virulence factors of Streptococcus uberis for a chimeric vaccine designSemantic proximity Read ↗

Group A streptococci induce stronger M protein-fibronectin interaction when specific human antibodies are boundSemantic proximity Read ↗

The group B streptococcal beta and pneumococcal Hic proteins are structurally related immune evasion molecules that bind the complement inhibitor factor H in an analogous fashion.Semantic proximity Read ↗

Same, Same, but Different: Molecular Analyses of <i>Streptococcus pneumoniae</i> Immune Evasion Proteins Identifies new Domains and Reveals Structural Differences between PspC and Hic VariantsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.