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Article

Opsonophagocytosis-inhibiting mac protein of group a streptococcus: identification and characteristics of two genetic complexes.

Infection and immunity - 1 Dec 2002

Lei Benfang, DeLeo Frank R, Reid Sean D, Voyich Jovanka M, Magoun Loranne, Liu Mengyao, Braughton Kevin R, Ricklefs Stacy, Hoe Nancy P, Cole Robert L, Leong John M, Musser James M

Abstract excerpt

Recently, it was reported that a streptococcal Mac protein (designated Mac(5005)) made by serotype M1 group A Streptococcus (GAS) is a homologue of human CD11b that inhibits opsonophagocytosis and killing of GAS by human polymorphonuclear leukocytes (PMNs) (B. Lei, F. R. DeLeo, N. P. Hoe, M. R. Graham, S. M. Mackie, R. L. Cole, M. Liu, H. R. Hill, D. E. Low, M. J. Federle, J. R. Scott, and J. M. Musser, Nat. Med....

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Identifiers

PMID: 12438365
DOI: 10.1128/IAI.70.12.6880-6890.2002
PMCID: PMC133040

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