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Article

Effects of Δ9-tetrahydrocannabinol in individuals with a familial vulnerability to alcoholism.

Psychopharmacology - 1 Jun 2014

Ranganathan Mohini, Sewell R Andrew, Carbuto Michelle, Elander Jacqueline, Schnakenberg Ashley, Radhakrishnan Rajiv, Pittman Brian, D'Souza Deepak Cyril

Abstract excerpt

BACKGROUND AND AIMS: A family history (FH) of alcoholism accounts for approximately 50% of the risk of developing alcohol problems. Several lines of preclinical evidence suggest that brain cannabinoid receptor (CB1R) function may mediate the effects of alcohol and risk for developing alcoholism including the observations that reduced CB1R function decreases alcohol-related behaviors and enhanced CB1R function...

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Identifiers

PMID: 24424782
DOI: 10.1007/s00213-013-3402-4

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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