Article
Family history of alcoholism influences naltrexone-induced reduction in alcohol drinking.
Biological psychiatry - 15 Sept 2007
Krishnan-Sarin Suchitra, Krystal John H, Shi Julia, Pittman Brian, O'Malley Stephanie S
Abstract excerpt
BACKGROUND: The purpose of this study was to examine the interactive effects of family history of alcoholism (FH+, FH-) and naltrexone dose (0, 50, 100 mg/day) on alcohol drinking. METHODS: Ninety-two, non-treatment-seeking alcohol-dependent participants received naltrexone daily for 6 days. On the 6th day, they participated in a laboratory paradigm involving exposure to a priming dose of alcohol followed by a...
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