Family history of alcoholism influences naltrexone-induced reduction in alcohol drinking.

doi:10.1016/j.biopsych.2006.11.018

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Back to search

Article

Family history of alcoholism influences naltrexone-induced reduction in alcohol drinking.

Biological psychiatry - 15 Sept 2007

Krishnan-Sarin Suchitra, Krystal John H, Shi Julia, Pittman Brian, O'Malley Stephanie S

Abstract excerpt

BACKGROUND: The purpose of this study was to examine the interactive effects of family history of alcoholism (FH+, FH-) and naltrexone dose (0, 50, 100 mg/day) on alcohol drinking. METHODS: Ninety-two, non-treatment-seeking alcohol-dependent participants received naltrexone daily for 6 days. On the 6th day, they participated in a laboratory paradigm involving exposure to a priming dose of alcohol followed by a...

Topics

Adult
Alcohol Drinking
Alcoholism
Behavior, Addictive
Choice Behavior
Dose-Response Relationship, Drug
Family
Female
Genetic Predisposition to Disease
Humans
Male
Naltrexone
Narcotic Antagonists
Reward
Sex Factors
Treatment Outcome

Source

Open in PubMed

Identifiers

PMID: 17336941
DOI: 10.1016/j.biopsych.2006.11.018

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics