Article
Human genetics and responses to influenza vaccination: clinical implications.
American journal of pharmacogenomics : genomics-related research in drug development and clinical practice - 1 Jan 2004
Lambkin Robert, Novelli Patricia, Oxford John, Gelder Colin
Abstract excerpt
Influenza A and B viruses are negative-strand RNA viruses that cause regular outbreaks of respiratory disease and substantially impact on morbidity and mortality. Our primary defense against the influenza virus infection is provided by neutralizing antibodies that inhibit the function of the virus surface coat proteins hemagglutinin and neuraminidase. Production of these antibodies by B lymphocytes requires help...
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