Article
Association of HLA class II genes with clinical hyporesponsiveness to trivalent inactivated influenza vaccine in children.
Vaccine - 4 Feb 2013
Narwaney Komal J, Glanz Jason M, Norris Jill M, Fingerlin Tasha E, Hokanson John E, Rewers Marian, Hambidge Simon J
Abstract excerpt
BACKGROUND: The primary prevention measure for influenza infection has been the use of influenza vaccines. However, even when the vaccine and circulating strains are well-matched, some healthy children do not respond to the vaccine, likely due to a genetic basis for immune hyporesponsiveness. The primary objective of this study was to identify HLA class II genes associated with clinical hyporesponsiveness after...
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