Article
Correlation between human leukocyte antigen class II alleles and HAI titers detected post-influenza vaccination.
PloS one - 1 Jan 2013
Moss Alastair J, Gaughran Fiona P, Karasu Aliyye, Gilbert Anthony S, Mann Alex J, Gelder Colin M, Oxford John S, Stephens Henry A, Lambkin-Williams Rob
Abstract excerpt
Influenza is a major cause of morbidity and mortality. Despite vaccination, many elderly recipients do not develop a protective antibody response. To determine whether Human Leukocyte Antigen (HLA) alleles modulate seroprotection to influenza, a cohort of HLA class II-typed high-risk vaccine recipients was investigated. Haemagglutinin inhibition (HAI) titres were measured 14-40 days post-subunit vaccination....
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