Article
Genetic stability of the attachment glycoprotein of human respiratory syncytial viruses during serial passages in cell cultures.
Acta virologica - 1 Jan 2004
de Sierra M, Arbiza J
Abstract excerpt
Thirteen isolates of human respiratory syncytial viruses (HRSV) of groups A and B were isolated in HEp-2 cells from nasopharyngeal aspirates (NPA) from the children with acute respiratory infections. Three isolates of HRSV of group A were propagated in HEp-2 cells in 20 serial passages. Nucleotide sequences of the products obtained by RT-PCR from the glycoprotein (G) hypervariable region of the original virus...
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