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Article

Respiratory syncytial virus grown in Vero cells contains a truncated attachment protein that alters its infectivity and dependence on glycosaminoglycans.

Journal of virology - 1 Oct 2009

Kwilas Steven, Liesman Rachael M, Zhang Liqun, Walsh Edward, Pickles Raymond J, Peeples Mark E

Abstract excerpt

Human respiratory syncytial virus (RSV) contains a heavily glycosylated 90-kDa attachment glycoprotein (G). Infection of HEp-2 and Vero cells in culture depends largely on virion G protein binding to cell surface glycosaminoglycans (GAGs). This GAG-dependent phenotype has been described for RSV grown in HEp-2 cells, but we have found that it is greatly reduced by a single passage in Vero cells. Virions produced...

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Identifiers

PMID: 19656891
DOI: 10.1128/JVI.00986-09
PMCID: PMC2753119

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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