Article
Microarray gene expression profiling of B-cell chronic lymphocytic leukemia subgroups defined by genomic aberrations and VH mutation status.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology - 1 Oct 2004
Haslinger Christian, Schweifer Norbert, Stilgenbauer Stephan, Döhner Hartmut, Lichter Peter, Kraut Norbert, Stratowa Christian, Abseher Roger
Abstract excerpt
PURPOSE: Genomic aberrations and mutational status of the immunoglobulin variable heavy chain (VH) gene have been shown to be among the most important predictors for outcome in patients with B-cell chronic lymphocytic leukemia (B-CLL). In this study, we report on differential gene expression patterns that are characteristic for genetically defined B-CLL subtypes. MATERIALS AND METHODS: One hundred genetically...
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