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Article

Involvement of a cytoplasmic-tail serine cluster in urotensin II receptor internalization.

The Biochemical journal - 1 Jan 2005

Proulx Christophe D, Simaan May, Escher Emanuel, Laporte Stéphane A, Guillemette Gaétan, Leduc Richard

Abstract excerpt

Most G-protein-coupled receptors that undergo agonist-dependent internalization require the presence of specific cytoplasmic-tail residues to initiate interactions with proteins of the endocytic machinery. Here we show that the UT receptor (urotensin II receptor) undergoes internalization, and that specific serine residues of the receptor's cytoplasmic tail participate in this process. We first observed a...

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Identifiers

PMID: 15458389
DOI: 10.1042/BJ20040807
PMCID: PMC1134679

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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