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Article

UP element-dependent transcription at the Escherichia coli rrnB P1 promoter: positional requirements and role of the RNA polymerase alpha subunit linker.

Nucleic acids research - 15 Oct 2001

Meng W, Belyaeva T, Savery N J, Busby S J, Ross W E, Gaal T, Gourse R L, Thomas M S

Abstract excerpt

The UP element stimulates transcription from the rrnB P1 promoter through a direct interaction with the C-terminal domain of the RNA polymerase alpha subunit (alphaCTD). We investigated the effect on transcription from rrnB P1 of varying both the location of the UP element and the length of the alpha subunit interdomain linker, separately and in combination. Displacement of the UP element by a single turn of the...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Share to Gene Expression Regulation, Bacterial

Share to Promoter Regions, Genetic

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Source

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Identifiers

PMID: 11600705
DOI: 10.1093/nar/29.20.4166
PMCID: PMC60210

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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