Article
Regulation and recognition of SCFGrr1 targets in the glucose and amino acid signaling pathways.
Molecular and cellular biology - 1 Oct 2004
Spielewoy Nathalie, Flick Karin, Kalashnikova Tatyana I, Walker John R, Wittenberg Curt
Abstract excerpt
SCFGrr1, one of several members of the SCF family of E3 ubiquitin ligases in budding Saccharomyces cerevisiae, is required for both regulation of the cell cycle and nutritionally controlled transcription. In addition to its role in degradation of Gic2 and the CDK targets Cln1 and Cln2, Grr1 is also required for induction of glucose- and amino acid-regulated genes. Induction of HXT genes by glucose requires the...
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