Article
Regulatory network connecting two glucose signal transduction pathways in Saccharomyces cerevisiae.
Eukaryotic cell - 1 Feb 2004
Kaniak Aneta, Xue Zhixiong, Macool Daniel, Kim Jeong-Ho, Johnston Mark
Abstract excerpt
The yeast Saccharomyces cerevisiae senses glucose, its preferred carbon source, through multiple signal transduction pathways. In one pathway, glucose represses the expression of many genes through the Mig1 transcriptional repressor, which is regulated by the Snf1 protein kinase. In another pathway, glucose induces the expression of HXT genes encoding glucose transporters through two glucose sensors on the cell...
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