Article
Phosphorylation by cAMP-dependent protein kinase is essential for synapsin-induced enhancement of neurotransmitter release in invertebrate neurons.
Journal of cell science - 1 Oct 2004
Fiumara Ferdinando, Giovedì Silvia, Menegon Andrea, Milanese Chiara, Merlo Daniela, Montarolo Pier Giorgio, Valtorta Flavia, Benfenati Fabio, Ghirardi Mirella
Abstract excerpt
Synapsins are synaptic vesicle-associated phosphoproteins involved in the regulation of neurotransmitter release and synapse formation; they are substrates for multiple protein kinases that phosphorylate them on distinct sites. We have previously found that injection of synapsin into Helix snail neurons cultured under low-release conditions increases the efficiency of neurotransmitter release. In order to...
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