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Article

Effects of PKA-mediated phosphorylation of Snapin on synaptic transmission in cultured hippocampal neurons.

The Journal of neuroscience : the official journal of the Society for Neuroscience - 21 Jul 2004

Thakur Pratima, Stevens David R, Sheng Zu-Hang, Rettig Jens

Abstract excerpt

Use-dependent activation of protein kinase A (PKA) modulates transmitter release, contributing to synaptic plasticity. Snapin, a PKA substrate in neurons, associates with the soluble N-ethylmaleimide-sensitive factor attachment protein receptor (SNARE) complex, and its phosphorylation leads to increased binding of synaptotagmin to the SNARE complex. We investigated the role of PKA-dependent phosphorylation of...

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Identifiers

PMID: 15269257
DOI: 10.1523/JNEUROSCI.0590-04.2004
PMCID: PMC6729866

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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