Article
Activation of EGL-47, a Galpha(o)-coupled receptor, inhibits function of hermaphrodite-specific motor neurons to regulate Caenorhabditis elegans egg-laying behavior.
The Journal of neuroscience : the official journal of the Society for Neuroscience - 29 Sept 2004
Moresco James J, Koelle Michael R
Abstract excerpt
Caenorhabditis elegans egg-laying behavior is inhibited by neurotransmitter signaling through the neural G-protein Galpha(o) and serves as a model for analyzing Galpha(o) signaling. Mutations that alter egg-laying frequency have identified genes encoding a number of signaling proteins that act with Galpha(o), but the receptors that activate Galpha(o) remain mostly uncharacterized. To further analyze Galpha(o)...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
