Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Multiple RGS proteins alter neural G protein signaling to allow C. elegans to rapidly change behavior when fed.

Genes & development - 15 Aug 2000

Dong M Q, Chase D, Patikoglou G A, Koelle M R

Abstract excerpt

Regulators of G protein signaling (RGS proteins) inhibit heterotrimeric G protein signaling by activating G protein GTPase activity. Many mammalian RGS proteins are expressed in the brain and can act in vitro on the neural G protein G(o), but the biological purpose of this multiplicity of regulators is not clear. We have analyzed all 13 RGS genes in Caenorhabditis elegans and found that three of them influence...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Behavior, Animal
Share to Caenorhabditis elegans
Share to Food

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to GTP-Binding Proteins

Share to Nervous System

Share to RGS Proteins

Share to Sequence Homology, Amino Acid

Share to Signal Transduction

Source

Open in PubMed Open full text

Identifiers

PMID: 10950865
PMCID: PMC316861

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Multiple RGS proteins alter neural G protein signaling to allow C. elegans to rapidly change behavior when fed.PMID 10950865Read ↗

Genetic analysis of RGS protein function in Caenorhabditis elegans.Semantic proximity Read ↗

An N-terminal region of Caenorhabditis elegans RGS proteins EGL-10 and EAT-16 directs inhibition of G(alpha)o versus G(alpha)q signaling.Semantic proximity Read ↗

EGL-10 regulates G protein signaling in the C. elegans nervous system and shares a conserved domain with many mammalian proteins.Semantic proximity Read ↗

C. elegans G protein regulator RGS-3 controls sensitivity to sensory stimuli.Semantic proximity Read ↗

Antagonism between G(o)alpha and G(q)alpha in Caenorhabditis elegans: the RGS protein EAT-16 is necessary for G(o)alpha signaling and regulates G(q)alpha activity.Semantic proximity Read ↗

Participation of the protein Go in multiple aspects of behavior in C. elegans.Semantic proximity Read ↗

A novel gain-of-function mutant of the cyclic GMP-dependent protein kinase egl-4 affects multiple physiological processes in Caenorhabditis elegans.Semantic proximity Read ↗

RSBP-1 is a membrane-targeting subunit required by the Galpha(q)-specific but not the Galpha(o)-specific R7 regulator of G protein signaling in Caenorhabditis elegans.Semantic proximity Read ↗

RGS-7 completes a receptor-independent heterotrimeric G protein cycle to asymmetrically regulate mitotic spindle positioning in C. elegans.Semantic proximity Read ↗

IRK-1 potassium channels mediate peptidergic inhibition of Caenorhabditis elegans serotonin neurons via a G(o) signaling pathway.Semantic proximity Read ↗

The G-protein beta-subunit GPB-2 in Caenorhabditis elegans regulates the G(o)alpha-G(q)alpha signaling network through interactions with the regulator of G-protein signaling proteins EGL-10 and EAT-16.Semantic proximity Read ↗

FMRFamide neuropeptides and acetylcholine synergistically inhibit egg-laying by C. elegans.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.