Article
An activating mutation in a Caenorhabditis elegans Gs protein induces neural degeneration.
Genes & development - 15 Jun 1997
Korswagen H C, Park J H, Ohshima Y, Plasterk R H
Abstract excerpt
Heterotrimeric guanine nucleotide-binding proteins (G proteins) act as signal-transducing molecules that connect serpentine-transmembrane receptors to a variety of intracellular effectors. We characterized a Caenorhabditis elegans G(s) gene, gsa-1, which encodes a G(s) alpha-subunit (G alpha(s))...
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