Article
Increase in Ty1 cDNA recombination in yeast sir4 mutant strains at high temperature.
Genetics - 1 Sept 2004
Radford Sarah J, Boyle Meredith L, Sheely Catherine J, Graham Joel, Haeusser Daniel P, Zimmerman Leigh, Keeney Jill B
Abstract excerpt
Transposition of the Ty1 element of the yeast Saccharomyces cerevisiae is temperature sensitive. We have identified a null allele of the silent information regulator gene SIR4 as a host mutant that allows for transposition at high temperature. We show that the apparent increase in transposition activity in sir4 mutant strains at high temperature is dependent on the RAD52 gene and is thus likely resulting from an...
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