Article
Multiple V1/V2 env variants are frequently present during primary infection with human immunodeficiency virus type 1.
Journal of virology - 1 Oct 2004
Ritola Kimberly, Pilcher Christopher D, Fiscus Susan A, Hoffman Noah G, Nelson Julie A E, Kitrinos Kathryn M, Hicks Charles B, Eron Joseph J, Swanstrom Ronald
Abstract excerpt
Human immunodeficiency virus type 1 (HIV-1) exists as a complex population of multiple genotypic variants in persons with chronic infection. However, acute HIV-1 infection via sexual transmission is a low-probability event in which there is thought to be low genetic complexity in the initial inoculum. In order to assess the viral complexity present during primary HIV-1 infection, the V1/V2 and V3 variable regions...
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