Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Detection and functional analysis of an SNP in the promoter of the human ferritin H gene that modulates the gene expression.

Gene - 1 Aug 2006

Faniello Maria Concetta, Fregola Annalisa, Nisticò Antonia, Quaresima Barbara, Crugliano Telma, Faraonio Raffaella, Puzzonia Pasquale, Baudi Francesco, Parlato Giuseppe, Cuda Giovanni, Morrone Giovanni, Venuta Salvatore, Costanzo Francesco

Abstract excerpt

The H ferritin promoter spans approximately 150 bp, upstream of the transcription start and is composed by two cis-elements in position -132 (A box) and -62 (B-box), respectively. The A box is recognized by the transcription factor Sp1, and the B-box by a protein complex called Bbf, which includes the CAAT binding factor NF-Y. In this study we performed a functional analysis of an H ferritin promoter allele...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Binding Sites
Share to CCAAT-Binding Factor

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Ferritins

Share to Gene Expression

Share to HeLa Cells

Share to In Vitro Techniques

Share to Sp1 Transcription Factor

Share to Transcription, Genetic

Source

Identifiers

PMID: 16797877
DOI: 10.1016/j.gene.2006.02.034

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Detection and functional analysis of an SNP in the promoter of the human ferritin H gene that modulates the gene expression.PMID 16797877Read ↗

Single nucleotide polymorphism in 5'-flanking region reduces transcription of surfactant protein B gene in H441 cells.Semantic proximity Read ↗

A negative cis-acting G-fer element participates in the regulation of expression of the human H-ferritin-encoding gene (FERH).Semantic proximity Read ↗

Upstream stimulatory factors are involved in the P1 promoter directed transcription of the A beta H-J-J locus.Semantic proximity Read ↗

The Human Reduced Folate Carrier Gene Is Regulated by the AP2 and Sp1 Transcription Factor Families and a Functional 61-Base Pair PolymorphismSemantic proximity Read ↗

Intronic SNP rs3811647 of the human transferrin gene modulates its expression in hepatoma cells.Semantic proximity Read ↗

Single nucleotide polymorphism analysis and functional characterization of the human Ah receptor (AhR) gene promoter.Semantic proximity Read ↗

Promoter Assay Using Luciferase Reporter Gene in the A549 Cell Line.Semantic proximity Read ↗

Characterization of human collagen XVIII promoter 2: interaction of Sp1, Sp3 and YY1 with the regulatory region and a SNP that increases transcription in hepatocytes.Semantic proximity Read ↗

Preliminary characterisation of the promoter of the human p22(phox) gene: identification of a new polymorphism associated with hypertension.Semantic proximity Read ↗

Genes for the human mitochondrial trifunctional protein alpha- and beta-subunits are divergently transcribed from a common promoter region.Semantic proximity Read ↗

Polymorphism and deficiency of human factor H-related proteins p39 and p37.Semantic proximity Read ↗

Genetic study of the hepcidin gene (HAMP) promoter and functional analysis of the c.-582A > G variant.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.