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Article

Breast cancer in female carriers of ATM gene alterations: outcome of adjuvant radiotherapy.

Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology - 1 Sept 2004

Meyer Andreas, John Esther, Dörk Thilo, Sohn Christof, Karstens Johann H, Bremer Michael

Abstract excerpt

BACKGROUND AND PURPOSE: We analyzed the clinical outcome of breast cancer patients carrying sequence variants in the ATM gene who received postoperative radiotherapy after breast conservative surgery to test whether an increased cellular radiosensitivity may translate into enhanced tumor cell killing and thereby result in an improvement of the therapeutic ratio. PATIENTS AND METHODS: We investigated a cohort of...

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Source

Identifiers

PMID: 15450731
DOI: 10.1016/j.radonc.2004.07.010

Genes

ATM

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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Breast cancer in female carriers of ATM gene alterations: outcome of adjuvant radiotherapy.PMID 15450731Read ↗

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The ATM gene and breast cancer: is it really a risk factor?Semantic proximity Read ↗

Possession of ATM Sequence Variants as Predictor for Late Normal Tissue Responses in Breast Cancer Patients Treated With RadiotherapySemantic proximity Read ↗

Variants in the ATM gene associated with a reduced risk of contralateral breast cancer.Semantic proximity Read ↗

Ataxia-telangiectasia gene (ATM) mutation heterozygosity in breast cancer: a narrative review.Semantic proximity Read ↗

Linkage disequilibrium pattern of the ATM gene in breast cancer patients and controls; association of SNPs and haplotypes to radio-sensitivity and post-lumpectomy local recurrenceSemantic proximity Read ↗

ATM haplotypes and cellular response to DNA damage: association with breast cancer risk and clinical radiosensitivity.Semantic proximity Read ↗

Single nucleotide polymorphism D1853N of the ATM gene may alter the risk for breast cancer.Semantic proximity Read ↗

The spectrum of ATM missense variants and their contribution to contralateral breast cancer.Semantic proximity Read ↗

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