Single nucleotide polymorphism D1853N of the ATM gene may alter the risk for breast cancer.

doi:10.1007/s00432-008-0355-9

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Article

Single nucleotide polymorphism D1853N of the ATM gene may alter the risk for breast cancer.

Journal of cancer research and clinical oncology - 1 Aug 2008

Schrauder M, Frank S, Strissel P L, Lux M P, Bani M R, Rauh C, Sieber C C, Heusinger K, Hartmann A, Schulz-Wendtland R, Strick R, Beckmann M W, Fasching Peter A

Abstract excerpt

PURPOSE: Various ATM (ataxia telangiectasia-mutated) mutations and polymorphisms have been reported to be associated with an increased breast cancer risk. Recent studies have produced contradictory results regarding the association between ATM genetic variants and breast cancer risk. MATERIALS AND METHODS: The common ATM polymorphism 5557G>A (p.D1853N) (rs1801516), previously suggested to be associated with...

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PMID: 18264724
DOI: 10.1007/s00432-008-0355-9

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