Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Gender-related association between the TGFB1+869 polymorphism and multiple sclerosis.

Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research - 1 Sept 2004

Schrijver Hans M, Crusius J Bart A, García-González M Asunçion, Polman Chris H, Peña A Salvador, Barkhof Frederik, Uitdehaag Bernard M J

Abstract excerpt

Our objective was to investigate whether polymorphisms and haplotypes in the TGFB1 gene are associated with susceptibility or disease characteristics of multiple sclerosis (MS). In 247 MS patients and 194 controls, single nucleotide polymorphisms (SNPs) at position +869 (Leu10Pro) and position +915 (Arg25Pro) in the signaling sequence of the TGFB1 gene were determined, and the distribution of alleles, genotypes,...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Base Sequence
Share to Demography

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Magnetic Resonance Imaging

Share to Molecular Sequence Data

Share to Multiple Sclerosis

Share to Sex Factors

Share to Transforming Growth Factor beta

Share to Transforming Growth Factor beta1

Source

Identifiers

PMID: 15450129
DOI: 10.1089/jir.2004.24.536

Genes

TGFB1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Gender-related association between the TGFB1+869 polymorphism and multiple sclerosis.PMID 15450129Read ↗

A link between promoter polymorphisms of the transforming growth factor β1 (TGFB1) and TGF-β1 receptor II (TGFBR2) genes and relapsing-remitting multiple sclerosis.Semantic proximity Read ↗

TGFB1 +869 T > C (rs1800470) variant is independently associated with susceptibility, laboratory activity, and TGF-β1 in patients with systemic lupus erythematosus.Semantic proximity Read ↗

Association of TGF-β1 +869C/T promoter polymorphism with susceptibility to autoimmune diseases: a meta-analysis.Semantic proximity Read ↗

TGF-β1 functional polymorphisms: a review.Semantic proximity Read ↗

TGF-β1 +869C/T polymorphism increases susceptibility to rheumatoid arthritis in North Indian population.Semantic proximity Read ↗

Association of transforming growth factor-β1 T869C, G915C, and C509T gene polymorphisms with rheumatoid arthritis risk.Semantic proximity Read ↗

TGF-β1 +869T/C (rs1982073) gene polymorphism and susceptibility to rheumatoid arthritis: Updated systematic review and meta-analysis.Semantic proximity Read ↗

Sequence variation in the transforming growth factor-beta1 (TGFB1) gene and multiple sclerosis susceptibility.Semantic proximity Read ↗

The functional class evaluated in rheumatoid arthritis is associated with soluble TGF-β1 serum levels but not with G915C (Arg25Pro) TGF-β1 polymorphism.Semantic proximity Read ↗

Association between transforming growth factor-beta1 T869C polymorphism and rheumatoid arthritis: a meta-analysis.Semantic proximity Read ↗

Transforming growth factor-beta1 869T/C, but not interleukin-6 -174G/C, polymorphism associates with hypertension in rheumatoid arthritis.Semantic proximity Read ↗

Association of a polymorphism of the transforming growth factor-beta1 gene with blood pressure in Japanese individuals.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.