Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The fibroblast growth factor receptor-4 Arg388 allele is associated with prostate cancer initiation and progression.

Clinical cancer research : an official journal of the American Association for Cancer Research - 15 Sept 2004

Wang Jianghua, Stockton David W, Ittmann Michael

Abstract excerpt

PURPOSE: Increased expression of fibroblast growth factors that can activate the fibroblast growth factor receptor-4 (FGFR-4) occurs in a substantial fraction of human prostate cancers in vivo. A germline polymorphism of the FGFR-4 gene resulting in expression of arginine at codon 388 (Arg388) is associated with aggressive disease in patients with breast and colon cancer. We therefore sought to determine whether...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Drug Combinations
Share to Glycine

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Laminin

Share to Proteoglycans

Share to Receptor, Fibroblast Growth Factor, Type 4

Share to Receptors, Fibroblast Growth Factor

Share to Receptors, Urokinase Plasminogen Activator

Share to Wound Healing

Source

Identifiers

PMID: 15448004
DOI: 10.1158/1078-0432.CCR-04-0408

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The fibroblast growth factor receptor-4 Arg388 allele is associated with prostate cancer initiation and progression.PMID 15448004Read ↗

FGFR4 Gly388Arg polymorphism contributes to prostate cancer development and progression: a meta-analysis of 2618 cases and 2305 controls.Semantic proximity Read ↗

FGFR-4 Arg³⁸⁸ enhances prostate cancer progression via extracellular signal-related kinase and serum response factor signaling.Semantic proximity Read ↗

Altered fibroblast growth factor receptor 4 stability promotes prostate cancer progression.Semantic proximity Read ↗

Selective over-expression of fibroblast growth factor receptors 1 and 4 in clinical prostate cancer.Semantic proximity Read ↗

FGFR4 Gly388Arg polymorphism and prostate cancer risk in Scottish men.Semantic proximity Read ↗

Association of FGFR4 genetic polymorphisms with prostate cancer risk and prognosis.Semantic proximity Read ↗

Association between fibroblast growth factor receptor-4 gene polymorphism and risk of prostate cancer: a meta-analysis.Semantic proximity Read ↗

Cancer progression and tumor cell motility are associated with the FGFR4 Arg(388) allele.Semantic proximity Read ↗

Effects of FGFR4 G388R, V10I polymorphisms on the likelihood of cancer.Semantic proximity Read ↗

New concept on association of FGFR4 G388R, V10I polymorphisms and risk of cancerSemantic proximity Read ↗

An updated meta-analysis of the association between fibroblast growth factor receptor 4 polymorphisms and susceptibility to cancer.Semantic proximity Read ↗

Polymorphisms of fibroblast growth factor receptor 4 have association with the development of prostate cancer and benign prostatic hyperplasia and the progression of prostate cancer in a Japanese population.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.