Article
Altered fibroblast growth factor receptor 4 stability promotes prostate cancer progression.
Neoplasia (New York, N.Y.) - 1 Aug 2008
Wang Jianghua, Yu Wendong, Cai Yi, Ren Chengxi, Ittmann Michael M
Abstract excerpt
Fibroblast growth factor receptor 4 (FGFR-4) is expressed at significant levels in almost all human prostate cancers, and expression of its ligands is ubiquitous. A common polymorphism of FGFR-4 in which arginine (Arg(388)) replaces glycine (Gly(388)) at amino acid 388 is associated with progress...
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