Article
Participation of the intron in the reaction catalyzed by the Xenopus tRNA splicing endonuclease.
Science (New York, N.Y.) - 13 Mar 1992
Baldi M I, Mattoccia E, Bufardeci E, Fabbri S, Tocchini-Valentini G P
Abstract excerpt
Introns have generally been assumed to be passive in the transfer RNA splicing reaction. Experiments have now been done showing that the endonuclease is able to cut a precursor provided that a base in the single-stranded loop of the intron can pair with the base of the 5' exon situated at the pos...
Topics
- Animals
- Base Sequence
- Binding Sites
- Endoribonucleases
- Exons
- Introns
- Molecular Sequence Data
- Mutation
- Nucleic Acid Conformation
- RNA Precursors
- RNA Splicing
- RNA, Transfer