Article
Characterization of the I-Spom I endonuclease from fission yeast: insights into the evolution of a group I intron-encoded homing endonuclease.
Journal of molecular evolution - 1 Sept 2002
Pellenz Stefan, Harington Alexis, Dujon Bernard, Wolf Klaus, Schäfer Bernd
Abstract excerpt
The first group I intron in the cox1 gene (cox1I1b ) of the mitochondrial genome of the fission yeast Schizosaccharomyces pombe is a mobile DNA element. The mobility is dependent on an endonuclease protein that is encoded by an intronic open reading frame (ORF). The intron-encoded endonuclease is a typical member of the LAGLIDADG protein family of endonucleases with two consensus motifs. In addition to this,...
Topics
- Cloning, Molecular
- Cyclooxygenase 1
- Deoxyribonuclease I
- Deoxyribonucleases, Type II Site-Specific
- Endonucleases
- Escherichia coli
- Evolution, Molecular
- Introns
- Isoenzymes
- Mutation
- Nucleic Acid Conformation
- Prostaglandin-Endoperoxide Synthases
- RNA, Fungal