Inhibition of chemical carcinogenesis in vivo by azatyrosine.

Article

Inhibition of chemical carcinogenesis in vivo by azatyrosine.

Cancer research - 15 Mar 1992

Izawa M, Takayama S, Shindo-Okada N, Doi S, Kimura M, Katsuki M, Nishimura S

Abstract excerpt

A single painting of 7,12-dimethylbenz[a]anthracene on the skin of transgenic mice harboring the human protooncogene c-Ha-ras induced papillomas at 100% incidence after 20 weeks (M. Izawa et al., unpublished data). Application of L-beta-(5-hydroxy-2-pyridyl)alanine (azatyrosine) to the skin at a...

Topics

9,10-Dimethyl-1,2-benzanthracene
Alanine
Animals
Antibiotics, Antineoplastic
Drug Screening Assays, Antitumor
Genes, ras
Methylnitrosourea
Mice
Mutation
Papilloma
Skin Neoplasms
Stomach Neoplasms

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