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Article

Inhibition of chemical carcinogenesis in vivo by azatyrosine.

Cancer research - 15 Mar 1992

Izawa M, Takayama S, Shindo-Okada N, Doi S, Kimura M, Katsuki M, Nishimura S

Abstract excerpt

A single painting of 7,12-dimethylbenz[a]anthracene on the skin of transgenic mice harboring the human protooncogene c-Ha-ras induced papillomas at 100% incidence after 20 weeks (M. Izawa et al., unpublished data). Application of L-beta-(5-hydroxy-2-pyridyl)alanine (azatyrosine) to the skin at a dose of 2 mg/mouse once every 3 days after initiation with 7,12-dimethylbenz[a]anthracene greatly reduced the...

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PMID: 1540971

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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