Article
Natural history and age at onset of hereditary breast cancer.
Cancer - 15 Mar 1992
Lynch H T, Watson P, Conway T A, Lynch J F
Abstract excerpt
Hereditary breast cancer (HBC) is noteworthy for certain unique facets of its natural history and heterogeneity. Interfamily heterogeneity in age at initial breast cancer diagnosis was investigated in 217 family members with HBC. The mean age at diagnosis was 44.9 years (standard deviation +/- 12.5 years). A one-way analysis of variance in ages at diagnosis, using the family as a random effect factor, indicated...
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