Natural history and age at onset of hereditary breast cancer.

doi:10.1002/1097-0142(19920315)69:6<1404::aid-cncr2820690616>3.0.co;2-r

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Article

Natural history and age at onset of hereditary breast cancer.

Cancer - 15 Mar 1992

Lynch H T, Watson P, Conway T A, Lynch J F

Abstract excerpt

Hereditary breast cancer (HBC) is noteworthy for certain unique facets of its natural history and heterogeneity. Interfamily heterogeneity in age at initial breast cancer diagnosis was investigated in 217 family members with HBC. The mean age at diagnosis was 44.9 years (standard deviation +/- 12...

Topics

Adult
Age Factors
Aged
Aged, 80 and over
Analysis of Variance
Breast Neoplasms
Carcinoma
Female
Genes, Dominant
Genetic Predisposition to Disease
Humans
Logistic Models
Middle Aged
Oncogenes
Ovarian Neoplasms
Pedigree
Regression Analysis
Syndrome

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