Article
BRCA mutations, molecular markers, and clinical variables in early-onset breast cancer: a population-based study.
Breast (Edinburgh, Scotland) - 1 Jun 2007
Musolino Antonino, Bella Maria A, Bortesi Beatrice, Michiara Maria, Naldi Nadia, Zanelli Paola, Capelletti Marzia, Pezzuolo Debora, Camisa Roberta, Savi Mario, Neri Tauro M, Ardizzoni Andrea
Abstract excerpt
Early age at onset is generally considered an indicator of genetic susceptibility to breast cancer. To address both the proportion of early-onset breast cancer associated with BRCA-1 or BRCA-2 germline mutation and the contribution of germline mutations to the clinical features and outcome of these tumors, we analyzed molecular status and clinical variables of a population-based sample of 66 Italian women...
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