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Article

Hypoxic induction of vascular endothelial growth factor is selectively impaired in mice carrying the mutant SOD1 gene.

Brain research - 7 Nov 2003

Murakami Tetsuro, Ilieva Hristelina, Shiote Mito, Nagata Tetsuya, Nagano Isao, Shoji Mikio, Abe Koji

Abstract excerpt

Localization and hypoxic induction of vascular endothelial growth factor (VEGF) was examined in the spinal cord of transgenic mice carrying a mutation in the superoxide dismutase 1 gene. Immunohistochemical and immunofluorescent study demonstrated that VEGF is mainly expressed in motor neurons before and after hypoxia. Baseline expression of VEGF was higher in transgenic (Tg) mice than in wild-type (Wt)...

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Source

Identifiers

PMID: 14556945
DOI: 10.1016/s0006-8993(03)03374-2

Genes

SOD1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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