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Article

Linkage to chromosome 14q in Alzheimer's disease (AD) patients without psychotic symptoms.

American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics - 5 Jan 2005

Avramopoulos Dimitrios, Fallin M Daniele, Bassett Susan S

Abstract excerpt

Cases of early onset AD have been attributed to three genes, PSEN1, PSEN2, and APP, while the only gene consistently associated with late onset AD (LOAD) is APOE. Several genome scans have now been performed for LOAD with inconsistent findings in several genomic regions, possibly reflecting the underlying genetic heterogeneity. Many lines of evidence suggest that the absence or presence of psychotic symptoms,...

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Source

Identifiers

PMID: 15389761
DOI: 10.1002/ajmg.b.30074

Genes

PSEN1
APOE
APP
PSEN2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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