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Article

Modulation of cell migration by integrin-mediated cytoskeletal linkages and ligand-binding affinity.

The Journal of cell biology - 1 Sept 1996

Huttenlocher A, Ginsberg M H, Horwitz A F

Abstract excerpt

Integrin cell surface adhesion receptors play a central role in mediating cell migration. We have developed a model system consisting of CHO cells ectopically expressing the alpha IIb beta 3 integrin to study integrin affinity and cytoskeletal interactions during cell migration. The alpha IIb beta 3 integrins are suited for study of integrin receptors during cell migration because they are well characterized with...

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Identifiers

PMID: 8830782
DOI: 10.1083/jcb.134.6.1551
PMCID: PMC2121008

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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