Article
The molecular profile of gastric intraepithelial foveolar type neoplasia based on somatic copy number alterations and multiple mutation analysis.
Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association - 1 Nov 2024
Sugai Tamotsu, Uesugi Noriyuki, Osakabe Mitsumasa, Yamamoto Ryuya, Hamada Koichi, Honda Michitaka, Yanagawa Naoki, Suzuki Hiromu
Abstract excerpt
BACKGROUND: Gastric foveolar type neoplasia is a rare histological variant of gastric tumors. It is very difficult to differentiate between benign and malignant intraepithelial foveolar neoplasia (IFN). Although limited molecular alterations have been identified in IFNs, somatic copy number alterations (SCNAs), which are linked to tumor progression, have not been systematically evaluated in IFN. METHODS: The aim...
Topics
- Humans
- Stomach Neoplasms
- DNA Copy Number Variations
- Female
- Male
- Aged
- Middle Aged
- Mutation
- DNA Mutational Analysis
- Carcinoma in Situ