Article
MnSOD polymorphism and breast cancer in a population-based case-control study.
Cancer letters - 10 Sept 2003
Egan Kathleen M, Thompson Patricia A, Titus-Ernstoff Linda, Moore Jason H, Ambrosone Christine B
Abstract excerpt
A polymorphism in the signal sequence (Ala-9Val) of the gene encoding the free radical-quenching manganese superoxide dismutase (MnSOD) has been reported to alter the risk for breast cancer. We evaluated this relationship in a population-based case-control study (476 breast cancer cases and 502 controls). Overall, relative risks were not significantly elevated in women with one (RR: 1.27; 95% CI: 0.91-1.77) or...
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