Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The vimE gene downstream of vimA is independently expressed and is involved in modulating proteolytic activity in Porphyromonas gingivalis W83.

Infection and immunity - 1 Oct 2004

Vanterpool Elaine, Roy Francis, Fletcher Hansel M

Abstract excerpt

Regulation/activation of the Porphyromonas gingivalis gingipains is poorly understood. A unique 1.3-kb open reading frame downstream of the bcp-recA-vimA transcriptional unit was cloned, insertionally inactivated with the ermF-ermAM antibiotic resistance cassette, and used to create a defective mutant by allelic exchange. In contrast to the wild-type W83 strain, the growth rate of the mutant strain (designated...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adhesins, Bacterial
Share to Cysteine Endopeptidases

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Gene Order

Share to Hemagglutinins

Share to Hemolysis

Share to Porphyromonas gingivalis

Share to Protein Precursors

Source

Open in PubMed Open full text

Identifiers

PMID: 15385452
DOI: 10.1128/IAI.72.10.5555-5564.2004
PMCID: PMC517529

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The vimE gene downstream of vimA is independently expressed and is involved in modulating proteolytic activity in Porphyromonas gingivalis W83.PMID 15385452Read ↗

Inactivation of vimF, a putative glycosyltransferase gene downstream of vimE, alters glycosylation and activation of the gingipains in Porphyromonas gingivalis W83.Semantic proximity Read ↗

Gingipain RgpB is excreted as a proenzyme in the vimA-defective mutant Porphyromonas gingivalis FLL92.Semantic proximity Read ↗

VimA is part of the maturation pathway for the major gingipains of Porphyromonas gingivalis W83.Semantic proximity Read ↗

Altered gingipain maturation in vimA- and vimE-defective isogenic mutants of Porphyromonas gingivalis.Semantic proximity Read ↗

The bcp gene in the bcp-recA-vimA-vimE-vimF operon is important in oxidative stress resistance in Porphyromonas gingivalis W83.Semantic proximity Read ↗

Porphyromonas gingivalis Gingipains: The Molecular Teeth of a Microbial VampireSemantic proximity Read ↗

Virulence of a Porphyromonas gingivalis W83 mutant defective in the prtH gene.Semantic proximity Read ↗

Molecular genetics and nomenclature of proteases of Porphyromonas gingivalisSemantic proximity Read ↗

Generation of lys-gingipain protease activity in Porphyromonas gingivalis W50 is independent of Arg-gingipain protease activities.Semantic proximity Read ↗

Altered expression and modification of proteases from an avirulent mutant of Porphyromonas gingivalis W50 (W50/BE1).Semantic proximity Read ↗

In Porphyromonas gingivalis VimF is involved in gingipain maturation through the transfer of galactose.Semantic proximity Read ↗

C-terminal domain residues important for secretion and attachment of RgpB in Porphyromonas gingivalis.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.