Article
In Porphyromonas gingivalis VimF is involved in gingipain maturation through the transfer of galactose.
PloS one - 1 Jan 2013
Muthiah Arun S, Aruni Wilson, Robles Antonette G, Dou Yuetan, Roy Francis, Fletcher Hansel M
Abstract excerpt
Previously, we have reported that gingipain activity in Porphyromonas gingivalis, the major causative agent in adult periodontitis, is post-translationally regulated by the unique Vim proteins including VimF, a putative glycosyltransferase. To further characterize VimF, an isogenic mutant defective in this gene in a different P. gingivalis genetic background was evaluated. In addition, the recombinant VimF...
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