Article
VimA is part of the maturation pathway for the major gingipains of Porphyromonas gingivalis W83.
Microbiology (Reading, England) - 1 Nov 2006
Vanterpool E, Roy F, Zhan W, Sheets S M, Sangberg L, Fletcher H M
Abstract excerpt
The authors have shown previously that the vimA gene, which is part of the bcp-recA-vimA operon, plays an important role in protease activation in Porphyromonas gingivalis. The gingipain RgpB proenzyme is secreted in the vimA-defective mutant P. gingivalis FLL92. An important question that is raised is whether the vimA gene product could directly interact with the proteases for their activation or regulate a...
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