Article
Virulence of a Porphyromonas gingivalis W83 mutant defective in the prtH gene.
Infection and immunity - 1 Apr 1995
Fletcher H M, Schenkein H A, Morgan R M, Bailey K A, Berry C R, Macrina F L
Abstract excerpt
In a previous study we cloned and determined the nucleotide sequence of the prtH gene from Porphyromonas gingivalis W83. This gene specifies a 97-kDa protease which is normally found in the membrane vesicles produced by P. gingivalis and which cleaves the C3 complement protein under defined condi...
Topics
- Alleles
- Animals
- Bacterial Proteins
- Base Sequence
- Complement C3
- Cysteine Endopeptidases
- DNA Primers
- DNA, Bacterial
- Gene Expression
- Genes, Bacterial
- Genetic Vectors
- Mice
- Molecular Sequence Data
- Mutation
- Porphyromonas gingivalis
- Restriction Mapping