Article
Altered expression and modification of proteases from an avirulent mutant of Porphyromonas gingivalis W50 (W50/BE1).
Microbiology (Reading, England) - 1 Sept 1998
Collinson Lucy M, Rangarajan Minnie, Curtis Michael A
Abstract excerpt
Proteases of Porphyromonas gingivalis are considered to be important factors in the virulence of this organism. A non-pigmenting mutant of P. gingivalis W50 (W50/BE1) has been shown to be less virulent in animal models and to produce significantly less Arg-specific protease activity than the pare...
Topics
- Amino Acid Sequence
- Animals
- Antibodies, Bacterial
- Arginine
- Bacterial Proteins
- Endopeptidases
- Gene Expression
- Genes, Bacterial
- Kinetics
- Molecular Sequence Data
- Mutation
- Porphyromonas gingivalis
- Protein Processing, Post-Translational
- Sequence Homology, Amino Acid
- Substrate Specificity
- Virulence