Article
Homologs of RUNX and CBF beta/PEBP2 beta in C. elegans.
Oncogene - 24 May 2004
Lee Junho, Ahnn Joohong, Bae Suk-Chul
Abstract excerpt
RUNX proteins are evolutionarily well-conserved transcription factors that are involved in essential aspects of the development of metazoan animals ranging from nematodes to humans. Genetic or epigenetic defects in any one of the three RUNX proteins in humans cause severe diseases. Although much is known about the functions and signaling pathways of the RUNX proteins through the use of mammalian systems, there...
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