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Article

Genetical and biochemical evidence for the involvement of the coprotease domain of Escherichia coli RecA protein in recombination.

Journal of molecular biology - 20 Feb 1992

Cazaux C, Defais M

Abstract excerpt

RecA amino acid residue 204 is involved in the coprotease domain of the protein responsible for the induction of mutagenic repair. Two mutations were created at this site leading to the addition of either a methyl or an isopropyl group on the original glycine. Analyses of both the in vivo and the in vitro properties of these mutated proteins demonstrated that this residue 204 is involved in many RecA activities,...

Topics

Adenosine Triphosphate
DNA Mutational Analysis
DNA Repair
DNA, Bacterial
Endopeptidases
Hydrogen Bonding
Phenotype
Rec A Recombinases
Recombination, Genetic
Structure-Activity Relationship

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Identifiers

PMID: 1538397
DOI: 10.1016/0022-2836(92)90243-d

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1538397-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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