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Article

Biochemical characterization of RecA variants that contribute to extreme resistance to ionizing radiation.

DNA repair - 1 Feb 2015

Piechura Joseph R, Tseng Tzu-Ling, Hsu Hsin-Fang, Byrne Rose T, Windgassen Tricia A, Chitteni-Pattu Sindhu, Battista John R, Li Hung-Wen, Cox Michael M

Abstract excerpt

Among strains of Escherichia coli that have evolved to survive extreme exposure to ionizing radiation, mutations in the recA gene are prominent and contribute substantially to the acquired phenotype. Changes at amino acid residue 276, D276A and D276N, occur repeatedly and in separate evolved populations. RecA D276A and RecA D276N exhibit unique adaptations to an environment that can require the repair of hundreds...

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Source

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Identifiers

PMID: 25559557
DOI: 10.1016/j.dnarep.2014.12.001
PMCID: PMC4308431

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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