Article
The BOADICEA model of genetic susceptibility to breast and ovarian cancer.
British journal of cancer - 18 Oct 2004
Antoniou A C, Pharoah P P D, Smith P, Easton D F
Abstract excerpt
Several genes conferring susceptibility to breast and ovarian cancer, notably BRCA1 and BRCA2, have been identified. The majority of the familial aggregation of breast cancer is, however, not explained by these genes. We have previously derived, using segregation analysis, a susceptibility model (BOADICEA, Breast and Ovarian Analysis of Disease Incidence and Carrier Estimation Algorithm) in which susceptibility...
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