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Article

Genetic diversity of the malaria vaccine candidate merozoite surface protein 1 gene of Plasmodium vivax field isolates in Republic of Korea.

Parasitology research - 1 Dec 2011

Han Eun-Taek, Wang Yue, Lim Chae Seung, Cho Jun Hwi, Chai Jong-Yil

Abstract excerpt

The Plasmodium vivax merozoite surface protein 1 (Pvmsp-1) locus codes for a major asexual blood-stage antigen currently proposed as a malaria vaccine candidate antigen. However, extensive polymorphism of this protein has been observed in isolates from different geographical areas. Here, we investigate the extent and the frequency of allelic diversity at the Pvmsp-1 locus in field isolates collected in the...

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PMID: 21556687
DOI: 10.1007/s00436-011-2413-5

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