Article
Association of estrogen receptor 1 intron 1 C/T polymorphism in Korean vitiligo patients.
Journal of dermatological science - 1 Sept 2004
Jin Sheng-Yu, Park Hyun-Ho, Li Guang-Zhe, Lee Hee Jae, Hong Mee-Suk, Park Hae-Jeong, Park Hun-Kuk, Seo Jung-Chul, Yim Sung-Vin, Chung Joo-Ho, Lee Mu-Hyoung
Abstract excerpt
BACKGROUND: Vitiligo is a common disease characterized by cutaneous white maculae due to loss of melanocytes. It is a polygenic disease, however, the exact pathogenesis of vitiligo is not yet known. The estrogen receptor (ESR) 1 gene was selected as a candidate gene because some researchers treated vitiligo successfully with the steroid-thyroid hormone mixture containing estrogen. Furthermore ESR was expressed in...
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